Early detection of periodontal disease
Early bacterial agent detection is useful to ascertain specific antibiotic for treatment. The diagnostic test is performed from a painless dental plaque sample. It is based on a molecular technique focused on identifying the group of bacteria in the sulcus between the tooth and gum.
After initial treatment, you can repeat the test to verify the effectiveness of therapy.
1. DNA extraction
2. PCR amplification
3. Hybridization using specific probes
Upon with a microbial infection, our body responds by activating immune system cells. White blood cells produce substances called interleukins (IL) involved in the inflammation process.
Genetically, some individuals produce more IL-1, generating a disproportionate inflammatory response to the microbial infection, resulting in highly destructive periodontitis.
The study of genetic predisposition to periodontal disease is useful both for the patients and for their descendants. It is important to know in advance which of the patient's children have inherited this genetic variation and to what extent, to take appropriate preventive measures before the disease appears. Taking preventive measures (maintenance of low plaque, strict teeth brushing and more frequent check-ups) can maintain healthy gums.
Echevarne Laboratory offers molecular techniques to help treatment and prevention periodontal disease. All we need is a saliva sample.